• L-92 on the symptoms and serum markers of atopic dermatitis in children.2011;154(3):236–45 International Archives of Allergy and Immunology Torii, S, et al. Effects of oral administration of Lactobacillus acidophilus
  • Effect of milk fermented with Lactobacillus acidophilus strain L-92 on symptoms of Japanese cedar pollen allergy: a randomized placebo controlled trial. 2005 Sep;69(9):1652–60, Bioscience Biotechnology Biochemistry Ishida, Y, et al.
  • Clinical effects of Lactobacillus acidophilus strain L-92 on perennial allergic rhinitis: a double-blind, placebo-controlled study. 2005 Feb;88(2):527–33, Journal of Dairy Science Ishida, Y, et al.
  • Effects of Oral Administration of Lactobacillus acidophilus L-92 on the Symptoms and Serum Cytokines of Atopic Dermatitis in Japanese Adults: A Double-Blind, Randomized, Clinical Trial. 2014;165(4):247-54, International Archives Allergy Immunology Inoue Y, et. al.
Graph showing improvement in skin severity score (SCORAD) and increased TGF-β levels in patients with atopic dermatitis after 8 weeks of L-92 probiotic supplementation compared to placebo.
Bar chart comparing cumulative days of cold symptoms such as cough, throat discomfort, hoarseness, chills, fatigue, and lassitude between L-92 and placebo groups, showing statistically significant reduction with L-92.
  • Subjects: 49 patients with Atopic dermatitis, aged ≧16 years
  • Test intervention: Tablet containing heat-sterilized L-92 (20.7 mg/day) or Placebo for 8 weeks
  • Results: Significant decrease in skin severity score and increase in TGF-β level
  • Subjects: 180 healthy adults suffered from an upper respiratory tract infection within the last 2 years 
  • Test Intervention: Tablet containing heat-sterilized L-92 (210 cells/day) or Placebo for 8 weeks
  • Results: Significant activation of pDCs and increase in fecal IgA level
Bar chart comparing IgA levels, showing L-92 probiotic significantly enhances immune function over placebo based on 8-week study.